On the probability of Neanderthal ancestry.
نویسنده
چکیده
منابع مشابه
The genomic landscape of Neanderthal ancestry in present-day humans
Genomic studies have shown thatNeanderthals interbredwithmodern humans,andthatnon-Africanstodayare theproductsof thismixture. The antiquity ofNeanderthal gene flow intomodernhumansmeans thatgenomic regions thatderive fromNeanderthals inanyonehuman todayareusually less thanahundredkilobases in size.However,Neanderthal haplotypes are also distinctive enough that several studies have been able to ...
متن کاملThe Strength of Selection against Neanderthal Introgression
Hybridization between humans and Neanderthals has resulted in a low level of Neanderthal ancestry scattered across the genomes of many modern-day humans. After hybridization, on average, selection appears to have removed Neanderthal alleles from the human population. Quantifying the strength and causes of this selection against Neanderthal ancestry is key to understanding our relationship to Ne...
متن کاملThe Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans
Some present-day humans derive up to ∼5% [1] of their ancestry from archaic Denisovans, an even larger proportion than the ∼2% from Neanderthals [2]. We developed methods that can disambiguate the locations of segments of Denisovan and Neanderthal ancestry in present-day humans and applied them to 257 high-coverage genomes from 120 diverse populations, among which were 20 individual Oceanians w...
متن کاملHigher levels of neanderthal ancestry in East Asians than in Europeans.
Neanderthals were a group of archaic hominins that occupied most of Europe and parts of Western Asia from ∼30,000 to 300,000 years ago (KYA). They coexisted with modern humans during part of this time. Previous genetic analyses that compared a draft sequence of the Neanderthal genome with genomes of several modern humans concluded that Neanderthals made a small (1-4%) contribution to the gene p...
متن کاملVariation and Functional Impact of Neanderthal Ancestry in Western Asia
Neanderthals contributed genetic material to modern humans via multiple admixture events. Initial admixture events presumably occurred in Western Asia shortly after humans migrated out of Africa. Despite being a focal point of admixture, earlier studies indicate lower Neanderthal introgression rates in some Western Asian populations as compared with other Eurasian populations. To better underst...
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عنوان ژورنال:
- American journal of human genetics
دوره 63 4 شماره
صفحات -
تاریخ انتشار 1998